Genome Editing Committee

The Genome Editing Committee designs annual ASGCT programming related to the development and application of genome editing technologies. This includes the optimization of safe and effective DNA and RNA editors, the continued discovery and innovation of naturally occurring enzymes that can be turned into useful tools, the development of precision editors capable of mutating individual bases or generating larger sequence edits such as exon or gene-sized insertions or replacements, methods to minimize unwanted off-target or genotoxic events, barriers facing broader adoption of these technologies, and the translation of these technologies into genetic medicines. Early genome editing clinical trials are already providing exciting results, and continued innovation in areas that span basic research, technology development, and pre-clinical studies will further allow these tools to help patients and their families.